The organic chemistry of drug design and drug action (3rd edition)
Richard B. Silverman, Northwestern University, Department of Chemistry, Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Evanston, Illinois, USA, Mark W. Holladay, Ambit Biosciences Corporation, Departments of Drug Discovery and Medicinal Chemistry, San Diego, California, USA.
- 3rd edition
- Amsterdam ; Boston Elsevier 2014
- xviii, 517 pages : illustrations
Includes bibliographical references and index.
Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems.