TY - BOOK AU - Silverman, Richard B AU - Holladay, Mark W TI - The organic chemistry of drug design and drug action (3rd edition) SN - 9780123820303 (alk. paper) AV - RS 403 Sil PY - 2014/// CY - Amsterdam ; Boston PB - Elsevier KW - BIOORGANIC CHEMISTRY KW - MOLECULAR PHARMACOLOGY KW - DRUGS--DESIGN KW - PHARMACEUTICAL CHEMISTRY N1 - Includes bibliographical references and index; Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems ER -